Van Wyk-Grumbach syndrome in a female pediatric patient with trisomy 21: a case report
نویسندگان
چکیده
منابع مشابه
A Case of Van Wyk-Grumbach Syndrome
In boys precocious puberty is defined as the development of secondary sexual characters before 9 year of age. In girls, the development of breasts (thelarche) before 7.5 year, the development of pubic hairs (pubarche) before 8.5 year or menarche before the age of 9.5 year is considered precocious [1]. Hypothyroidism is usually associated with delayed puberty and rarely with precocious puberty [...
متن کاملAn unusual presentation of girl with down syndrome: Van-Wyk Grumbach syndrome
Van Wyk-Grumbach syndrome is a rare disease characterized by precocious puberty associated with prolonged hypothyroidism and multicystic enlarged ovaries. A9 year-old girl with Down syndrome visited our hospital for early menarche. At birth, she showed subclinical hypothyroidism (11.8 mg/dL of thyroxine (T4) and 6.05 mIU/mL of thyroid stimulating hormone (TSH)), but she had not been followed up...
متن کاملELLIS-VAN CREVELD SYNDROME: REPORT OF A CASE IN AN ADULT PATIENT
Ellis-van Creveld syndrome is transmitted as an autosomal recessive trait. This syndrome is accompanied in 60% of cases with congenital heart disease, mostly single atrium or large ASD. Patients are mostly symptomatic, but in this rare case despite 68 years of age, the patient was free of symptoms except for complete heart block for which pacemaker was inserted
متن کاملLaryngeal Carcinoma in a Pediatric Patient - A Case Report
Introduction: Carcinoma of the larynx is an extremely uncommon clinical entity in pediatric age. The diagnosis of the laryngeal carcinoma is often delayed due to the low index of suspicion. The factors contributing to delayed diagnosis include the similarity of its symptoms to common benign lesions of the larynx in childhood and difficult examination of the larynx in pediatric patients. ...
متن کاملAn unusual presentation of acquired hypothyroidism: the Van Wyk-Grumbach syndrome.
The association in young females of long-standing primary hypothyroidism, isosexual precocious pseudopuberty and multicystic enlarged ovaries was first described in 1960 by Van Wyk and Grumbach. Since then, sporadic case reports have contributed to clarifying the key features of this syndrome. The unique elements that lead to this diagnosis are FSH-dominated sexual precocity combined with a del...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Pediatric Endocrinology
سال: 2020
ISSN: 1687-9856
DOI: 10.1186/s13633-020-0072-y